KIAA1217-FBXO18 Fusion FISH Probe
The KIAA1217-FBXO18 Fusion FISH Probe is used to confirm a fusion of the KIAA1217 and FBXO18 genes. The fusion of the KIAA1217 and FBXO18 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIAA1217-FBXO18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-RERE | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-REOR | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-REGO | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-REGR | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-REAQ | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-ORRE | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-OROR | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-ORGO | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GORE | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GOOR | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GOGO | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GOGR | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GRRE | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GROR | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GRGO | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GRGR | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-AQRE | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-AQOR | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-AQGO | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-AQGR | 20 (40 μL) | 200 μL |
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| KIAA1217-FBXO18-20-AQAQ | 20 (40 μL) | 200 μL |
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KIAA1217 Gene Summary
The (KIAA1217) gene is located on chr10 :23983674-24836772 at 10p12.2-p12.1.
Gene Name:
Chromosome: CHR10: 23983674 -24836772
Locus: 10p12.2-p12.1
FBXO18 Gene Summary
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: F-box Protein, Helicase, 18
Chromosome: CHR10: 5932213 -5979556
Locus: 10p15.1
Gene Diseases
The KIAA1217 FBXO18 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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