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KIAA0564-RICTOR Fusion FISH Probe

The KIAA0564-RICTOR Fusion FISH Probe is used to confirm a fusion of the KIAA0564 and RICTOR genes. The fusion of the KIAA0564 and RICTOR genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
KIAA0564-RICTOR-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-RERE 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-REOR 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-REGO 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-REGR 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-REAQ 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-ORRE 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-OROR 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-ORGO 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-ORAQ 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GORE 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GOOR 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GOGO 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GOGR 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GOAQ 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GRRE 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GROR 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GRGO 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GRGR 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-GRAQ 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-AQRE 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-AQOR 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-AQGO 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-AQGR 20 (40 μL) 200 μL
KIAA0564-RICTOR-20-AQAQ 20 (40 μL) 200 μL

RICTOR Gene Summary

RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008]

Gene Name: RPTOR Independent Companion Of MTOR Complex 2

Chromosome: CHR5: 38938021 -39074501

Locus: 5p13.1

Gene Diseases

The KIAA0564 RICTOR Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Correlation between immunohistochemistry and RICTOR FISH amplification in small cell lung carcinoma

Small cell lung carcinoma (SCLC) accounts for approximately 15% of all lung cancers and remains a challenging disease to treat, with no significant improvements in the development of targeted therapies. RICTOR is one of the most frequently amplified genes and a potential therapeutic target in SCLC. This study used IHC and Empire Genomics' RICTOR FISH probe to evaluate RICTOR overexpression and gene amplification in 100 SCLC tumors.
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Correlation between RICTOR overexpression and amplification in advanced solid tumors

RICTOR amplification is common across many solid tumors, and recent studies point to the gene as a potential targetable alteration. This study used IHC to measure RICTOR protein expression and our RICTOR FISH probe to detect RICTOR amplification in 213 advanced solid tumors. RICTOR was found overexpressed in 47% of tumors, and IHC and FISH results were closely correlated, indicating that RICTOR overexpression is associated with tumor progression.
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