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KIAA0564-RB1 Fusion FISH Probe

The KIAA0564-RB1 Fusion FISH Probe is used to confirm a fusion of the KIAA0564 and RB1 genes. The fusion of the KIAA0564 and RB1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KIAA0564-RB1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
KIAA0564-RB1-20-RERE 20 (40 μL) 200 μL
KIAA0564-RB1-20-REOR 20 (40 μL) 200 μL
KIAA0564-RB1-20-REGO 20 (40 μL) 200 μL
KIAA0564-RB1-20-REGR 20 (40 μL) 200 μL
KIAA0564-RB1-20-REAQ 20 (40 μL) 200 μL
KIAA0564-RB1-20-ORRE 20 (40 μL) 200 μL
KIAA0564-RB1-20-OROR 20 (40 μL) 200 μL
KIAA0564-RB1-20-ORGO 20 (40 μL) 200 μL
KIAA0564-RB1-20-ORAQ 20 (40 μL) 200 μL
KIAA0564-RB1-20-GORE 20 (40 μL) 200 μL
KIAA0564-RB1-20-GOOR 20 (40 μL) 200 μL
KIAA0564-RB1-20-GOGO 20 (40 μL) 200 μL
KIAA0564-RB1-20-GOGR 20 (40 μL) 200 μL
KIAA0564-RB1-20-GOAQ 20 (40 μL) 200 μL
KIAA0564-RB1-20-GRRE 20 (40 μL) 200 μL
KIAA0564-RB1-20-GROR 20 (40 μL) 200 μL
KIAA0564-RB1-20-GRGO 20 (40 μL) 200 μL
KIAA0564-RB1-20-GRGR 20 (40 μL) 200 μL
KIAA0564-RB1-20-GRAQ 20 (40 μL) 200 μL
KIAA0564-RB1-20-AQRE 20 (40 μL) 200 μL
KIAA0564-RB1-20-AQOR 20 (40 μL) 200 μL
KIAA0564-RB1-20-AQGO 20 (40 μL) 200 μL
KIAA0564-RB1-20-AQGR 20 (40 μL) 200 μL
KIAA0564-RB1-20-AQAQ 20 (40 μL) 200 μL

RB1 Gene Summary

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

Gene Name: RB Transcriptional Corepressor 1

Chromosome: CHR13: 48877882 -49056026

Locus: 13q14.2

Gene Diseases

The KIAA0564 RB1 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

The Utility of ERBB4 and RB1 Immunohistochemistry in Distinguishing Chromophobe Renal Cell Carcinoma From Renal Oncocytoma

Renal oncocytoma (RO) is a benign epithelial neoplasm that makes up about 5 to 9% of all renal cell tumors. RO can be difficult to distinguish from a closely related but malignant counterpart, chromophobe renal cell carcinoma (ChrCC). This study used both IHC and FISH to detect the presence of RB1 and ERBB4, two genes that have been found deleted in ChrCC but not RO. A total of 28 ChrCCs and 25 RO cases were tested. Empire Genomics’ RB1 and ERBB4 FISH probes were used to detect deletions in these genes.