KIAA0556-NECAB2 Fusion FISH Probe
The KIAA0556-NECAB2 Fusion FISH Probe is used to confirm a fusion of the KIAA0556 and NECAB2 genes. The fusion of the KIAA0556 and NECAB2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIAA0556-NECAB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-RERE | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-REOR | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-REGO | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-REGR | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-REAQ | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-ORRE | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-OROR | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-ORGO | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GORE | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GOOR | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GOGO | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GOGR | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GRRE | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GROR | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GRGO | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GRGR | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-AQRE | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-AQOR | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-AQGO | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-AQGR | 20 (40 μL) | 200 μL |
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| KIAA0556-NECAB2-20-AQAQ | 20 (40 μL) | 200 μL |
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KIAA0556 Gene Summary
This gene encodes a novel, evolutionarily conserved, ciliary protein. In human hTERT-RPE1 cells, the protein is found at the base of cilia, decorating the ciliary axoneme, and enriched at the ciliary tip. The protein binds to microtubules in vitro and regulates their stability when it is overexpressed. A null mutation in this gene has been associated with Joubert syndrome, a recessive disorder that is characterized by a distinctive mid-hindbrain and cerebellar malformation and is also often associated with wider ciliopathy symptoms. Consistently, in a serum-starvation ciliogenesis assay, human fibroblast cells derived from patients with the mutation display a reduced number of ciliated cells with abnormally long cilia. [provided by RefSeq, Feb 2016]
Gene Name:
Chromosome: CHR16: 27561467 -27791692
Locus: 16p12.1
NECAB2 Gene Summary
The protein encoded by this gene is a neuronal calcium-binding protein that binds to and modulates the function of at least two receptors, adenosine A(2A) receptor and metabotropic glutamate receptor type 5. [provided by RefSeq, Jul 2016]
Gene Name: N-terminal EF-hand Calcium Binding Protein 2
Chromosome: CHR16: 84002236 -84036379
Locus: 16q23.3
Gene Diseases
The KIAA0556 NECAB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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