KIAA0317-CELA3B Fusion FISH Probe
The KIAA0317-CELA3B Fusion FISH Probe is used to confirm a fusion of the KIAA0317 and CELA3B genes. The fusion of the KIAA0317 and CELA3B genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIAA0317-CELA3B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-RERE | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-REOR | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-REGO | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-REGR | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-REAQ | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-ORRE | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-OROR | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-ORGO | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GORE | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GOOR | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GOGO | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GOGR | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GRRE | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GROR | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GRGO | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GRGR | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-AQRE | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-AQOR | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-AQGO | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-AQGR | 20 (40 μL) | 200 μL |
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| KIAA0317-CELA3B-20-AQAQ | 20 (40 μL) | 200 μL |
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CELA3B Gene Summary
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009]
Gene Name: Chymotrypsin Like Elastase Family Member 3B
Chromosome: CHR1: 22303417 -22315847
Locus: 1p36.12
Gene Diseases
The KIAA0317 CELA3B Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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