KHSRP-CD70 Fusion FISH Probe
The KHSRP-CD70 Fusion FISH Probe is used to confirm a fusion of the KHSRP and CD70 genes. The fusion of the KHSRP and CD70 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KHSRP-CD70-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KHSRP-CD70-20-AQAQ | 20 (40 μL) | 200 μL |
|
CD70 Gene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
Gene Name: CD70 Molecule
Chromosome: CHR19: 6585849 -6591163
Locus: 19p13.3
KHSRP Gene Summary
The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010]
Gene Name: KH-type Splicing Regulatory Protein
Chromosome: CHR19: 6413118 -6424822
Locus: 19p13.3
Gene Diseases
The KHSRP CD70 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|