KDM6B-TMEM95 Fusion FISH Probe
The KDM6B-TMEM95 Fusion FISH Probe is used to confirm a fusion of the KDM6B and TMEM95 genes. The fusion of the KDM6B and TMEM95 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KDM6B-TMEM95-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KDM6B-TMEM95-20-AQAQ | 20 (40 μL) | 200 μL |
|
KDM6B Gene Summary
The protein encoded by this gene is a lysine-specific demethylase that specifically demethylates di- or tri-methylated lysine 27 of histone H3 (H3K27me2 or H3K27me3). H3K27 trimethylation is a repressive epigenetic mark controlling chromatin organization and gene silencing. This protein can also demethylate non-histone proteins such as retinoblastoma protein. Through its demethylation actvity this gene influences cellular differentiation and development, tumorigenesis, inflammatory diseases, and neurodegenerative diseases. This protein has two classical nuclear localization signals at its N-terminus. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Gene Name: Lysine Demethylase 6B
Chromosome: CHR17: 7743234 -7758118
Locus: 17p13.1
TMEM95 Gene Summary
The Transmembrane Protein 95 (TMEM95) gene is located on chr17 :7258496-7260538 at 17p13.1.
Gene Name: Transmembrane Protein 95
Chromosome: CHR17: 7258496 -7260538
Locus: 17p13.1
Gene Diseases
The KDM6B TMEM95 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|