KDM6A-ZNF674 Fusion FISH Probe
The KDM6A-ZNF674 Fusion FISH Probe is used to confirm a fusion of the KDM6A and ZNF674 genes. The fusion of the KDM6A and ZNF674 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KDM6A-ZNF674-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-RERE | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-REOR | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-REGO | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-REGR | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-REAQ | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-ORRE | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-OROR | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-ORGO | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-ORAQ | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GORE | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GOOR | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GOGO | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GOGR | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GOAQ | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GRRE | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GROR | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GRGO | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GRGR | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-GRAQ | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-AQRE | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-AQOR | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-AQGO | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-AQGR | 20 (40 μL) | 200 μL |
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| KDM6A-ZNF674-20-AQAQ | 20 (40 μL) | 200 μL |
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KDM6A Gene Summary
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Name: Lysine Demethylase 6A
Chromosome: CHRX: 44732422 -44971845
Locus: Xp11.3
ZNF674 Gene Summary
This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disabilities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]
Gene Name: Zinc Finger Protein 674
Chromosome: CHRX: 46357159 -46404892
Locus: Xp11.3
Gene Diseases
The KDM6A ZNF674 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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