KDM6A-RPS6KA3 Fusion FISH Probe
The KDM6A-RPS6KA3 Fusion FISH Probe is used to confirm a fusion of the KDM6A and RPS6KA3 genes. The fusion of the KDM6A and RPS6KA3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KDM6A-RPS6KA3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-RERE | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-REOR | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-REGO | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-REGR | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-REAQ | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-ORRE | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-OROR | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-ORGO | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-ORAQ | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GORE | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GOOR | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GOGO | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GOGR | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GOAQ | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GRRE | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GROR | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GRGO | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GRGR | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-GRAQ | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-AQRE | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-AQOR | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-AQGO | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-AQGR | 20 (40 μL) | 200 μL |
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| KDM6A-RPS6KA3-20-AQAQ | 20 (40 μL) | 200 μL |
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RPS6KA3 Gene Summary
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein S6 Kinase A3
Chromosome: CHRX: 20168028 -20284750
Locus: Xp22.12
KDM6A Gene Summary
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Name: Lysine Demethylase 6A
Chromosome: CHRX: 44732422 -44971845
Locus: Xp11.3
Gene Diseases
The KDM6A RPS6KA3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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