KDM6A-ARHGAP6 Fusion FISH Probe
The KDM6A-ARHGAP6 Fusion FISH Probe is used to confirm a fusion of the KDM6A and ARHGAP6 genes. The fusion of the KDM6A and ARHGAP6 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KDM6A-ARHGAP6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-RERE | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-REOR | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-REGO | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-REGR | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-REAQ | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-ORRE | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-OROR | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-ORGO | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-ORAQ | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GORE | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GOOR | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GOGO | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GOGR | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GOAQ | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GRRE | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GROR | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GRGO | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GRGR | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-GRAQ | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-AQRE | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-AQOR | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-AQGO | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-AQGR | 20 (40 μL) | 200 μL |
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| KDM6A-ARHGAP6-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGAP6 Gene Summary
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Rho GTPase Activating Protein 6
Chromosome: CHRX: 11155662 -11683821
Locus: Xp22.2
KDM6A Gene Summary
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Name: Lysine Demethylase 6A
Chromosome: CHRX: 44732422 -44971845
Locus: Xp11.3
Gene Diseases
The KDM6A ARHGAP6 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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