KDM5C-MAGT1 Fusion FISH Probe
The KDM5C-MAGT1 Fusion FISH Probe is used to confirm a fusion of the KDM5C and MAGT1 genes. The fusion of the KDM5C and MAGT1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KDM5C-MAGT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-RERE | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-REOR | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-REGO | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-REGR | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-REAQ | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-ORRE | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-OROR | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-ORGO | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GORE | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GOOR | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GOGO | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GOGR | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GRRE | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GROR | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GRGO | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GRGR | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-AQRE | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-AQOR | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-AQGO | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-AQGR | 20 (40 μL) | 200 μL |
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| KDM5C-MAGT1-20-AQAQ | 20 (40 μL) | 200 μL |
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KDM5C Gene Summary
This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Gene Name: Lysine Demethylase 5C
Chromosome: CHRX: 53220502 -53254604
Locus: Xp11.22
MAGT1 Gene Summary
This gene encodes a ubiquitously expressed magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause a form of X-linked intellectual disability (XLID). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jul 2017]
Gene Name: Magnesium Transporter 1
Chromosome: CHRX: 77081861 -77151065
Locus: Xq21.1
Gene Diseases
The KDM5C MAGT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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