KDM5A-IQSEC3 Fusion FISH Probe
The KDM5A-IQSEC3 Fusion FISH Probe is used to confirm a fusion of the KDM5A and IQSEC3 genes. The fusion of the KDM5A and IQSEC3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KDM5A-IQSEC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-RERE | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-REOR | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-REGO | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-REGR | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-REAQ | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-ORRE | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-OROR | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-ORGO | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GORE | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GOOR | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GOGO | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GOGR | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GRRE | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GROR | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GRGO | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GRGR | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-AQRE | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-AQOR | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-AQGO | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-AQGR | 20 (40 μL) | 200 μL |
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| KDM5A-IQSEC3-20-AQAQ | 20 (40 μL) | 200 μL |
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KDM5A Gene Summary
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]
Gene Name: Lysine Demethylase 5A
Chromosome: CHR12: 389222 -498620
Locus: 12p13.33
IQSEC3 Gene Summary
The IQ Motif And Sec7 Domain 3 (IQSEC3) gene is located on chr12 :176048-287625 at 12p13.33.
Gene Name: IQ Motif And Sec7 Domain 3
Chromosome: CHR12: 176048 -287625
Locus: 12p13.33
Gene Diseases
The KDM5A IQSEC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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