KDM4C-KLK7 Fusion FISH Probe
The KDM4C-KLK7 Fusion FISH Probe is used to confirm a fusion of the KDM4C and KLK7 genes. The fusion of the KDM4C and KLK7 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KDM4C-KLK7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KDM4C-KLK7-20-AQAQ | 20 (40 μL) | 200 μL |
|
KLK7 Gene Summary
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
Gene Name: Kallikrein Related Peptidase 7
Chromosome: CHR19: 51479734 -51487320
Locus: 19q13.41
KDM4C Gene Summary
This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: Lysine Demethylase 4C
Chromosome: CHR9: 6757640 -7175648
Locus: 9p24.1
Gene Diseases
The KDM4C KLK7 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|