KDM4A-FAF1 Fusion FISH Probe
The KDM4A-FAF1 Fusion FISH Probe is used to confirm a fusion of the KDM4A and FAF1 genes. The fusion of the KDM4A and FAF1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KDM4A-FAF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-RERE | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-REOR | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-REGO | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-REGR | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-REAQ | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-ORRE | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-OROR | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-ORGO | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GORE | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GOOR | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GOGO | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GOGR | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GRRE | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GROR | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GRGO | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GRGR | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-AQRE | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-AQOR | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-AQGO | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-AQGR | 20 (40 μL) | 200 μL |
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| KDM4A-FAF1-20-AQAQ | 20 (40 μL) | 200 μL |
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KDM4A Gene Summary
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009]
Gene Name: Lysine Demethylase 4A
Chromosome: CHR1: 44115796 -44171189
Locus: 1p34.2-p34.1
FAF1 Gene Summary
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008]
Gene Name: Fas Associated Factor 1
Chromosome: CHR1: 50906934 -51425936
Locus: 1p32.3
Gene Diseases
The KDM4A FAF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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