KDM4A-CREB3L4 Fusion FISH Probe
The KDM4A-CREB3L4 Fusion FISH Probe is used to confirm a fusion of the KDM4A and CREB3L4 genes. The fusion of the KDM4A and CREB3L4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KDM4A-CREB3L4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-RERE | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-REOR | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-REGO | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-REGR | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-REAQ | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-ORRE | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-OROR | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-ORGO | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-ORAQ | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GORE | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GOOR | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GOGO | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GOGR | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GOAQ | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GRRE | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GROR | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GRGO | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GRGR | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-GRAQ | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-AQRE | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-AQOR | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-AQGO | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-AQGR | 20 (40 μL) | 200 μL |
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| KDM4A-CREB3L4-20-AQAQ | 20 (40 μL) | 200 μL |
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KDM4A Gene Summary
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009]
Gene Name: Lysine Demethylase 4A
Chromosome: CHR1: 44115796 -44171189
Locus: 1p34.2-p34.1
CREB3L4 Gene Summary
This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: CAMP Responsive Element Binding Protein 3 Like 4
Chromosome: CHR1: 153940396 -153946832
Locus: 1q21.3
Gene Diseases
The KDM4A CREB3L4 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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