KDM2B-CORO1C Fusion FISH Probe
The KDM2B-CORO1C Fusion FISH Probe is used to confirm a fusion of the KDM2B and CORO1C genes. The fusion of the KDM2B and CORO1C genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KDM2B-CORO1C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-RERE | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-REOR | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-REGO | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-REGR | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-REAQ | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-ORRE | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-OROR | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-ORGO | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-ORAQ | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GORE | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GOOR | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GOGO | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GOGR | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GOAQ | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GRRE | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GROR | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GRGO | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GRGR | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-GRAQ | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-AQRE | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-AQOR | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-AQGO | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-AQGR | 20 (40 μL) | 200 μL |
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| KDM2B-CORO1C-20-AQAQ | 20 (40 μL) | 200 μL |
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CORO1C Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Name: Coronin 1C
Chromosome: CHR12: 109038886 -109125295
Locus: 12q24.11
KDM2B Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Lysine Demethylase 2B
Chromosome: CHR12: 121866899 -122018920
Locus: 12q24.31
Gene Diseases
The KDM2B CORO1C Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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