KCNQ5-CRYL1 Fusion FISH Probe
The KCNQ5-CRYL1 Fusion FISH Probe is used to confirm a fusion of the KCNQ5 and CRYL1 genes. The fusion of the KCNQ5 and CRYL1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCNQ5-CRYL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-RERE | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-REOR | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-REGO | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-REGR | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-REAQ | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-ORRE | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-OROR | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-ORGO | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GORE | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GOOR | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GOGO | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GROR | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GRGR | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-AQRE | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-AQOR | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-AQGO | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-AQGR | 20 (40 μL) | 200 μL |
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| KCNQ5-CRYL1-20-AQAQ | 20 (40 μL) | 200 μL |
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CRYL1 Gene Summary
The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye. [provided by RefSeq, Jul 2008]
Gene Name: Crystallin Lambda 1
Chromosome: CHR13: 20977805 -21100012
Locus: 13q12.11
KCNQ5 Gene Summary
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 5
Chromosome: CHR6: 73331570 -73908573
Locus: 6q13
Gene Diseases
The KCNQ5 CRYL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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