KCNQ3-ZHX2 Fusion FISH Probe
The KCNQ3-ZHX2 Fusion FISH Probe is used to confirm a fusion of the KCNQ3 and ZHX2 genes. The fusion of the KCNQ3 and ZHX2 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCNQ3-ZHX2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-RERE | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-REOR | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-REGO | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-REGR | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-REAQ | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-ORRE | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-OROR | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-ORGO | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-ORAQ | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GORE | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GOOR | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GOGO | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GOAQ | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GROR | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GRGR | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-GRAQ | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-AQRE | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-AQOR | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-AQGO | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-AQGR | 20 (40 μL) | 200 μL |
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| KCNQ3-ZHX2-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNQ3 Gene Summary
This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 3
Chromosome: CHR8: 133133104 -133493004
Locus: 8q24.22
ZHX2 Gene Summary
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Fingers And Homeoboxes 2
Chromosome: CHR8: 123793900 -123986755
Locus: 8q24.13
Gene Diseases
The KCNQ3 ZHX2 Fusion has been associated with the following diseases:
| Disease Name |
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| Thymoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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