KCNMB4-RTKN2 Fusion FISH Probe
The KCNMB4-RTKN2 Fusion FISH Probe is used to confirm a fusion of the KCNMB4 and RTKN2 genes. The fusion of the KCNMB4 and RTKN2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCNMB4-RTKN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-RERE | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-REOR | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-REGO | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-REGR | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-REAQ | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-ORRE | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-OROR | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-ORGO | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GORE | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GOOR | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GOGO | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GROR | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GRGR | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-AQRE | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-AQOR | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-AQGO | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-AQGR | 20 (40 μL) | 200 μL |
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| KCNMB4-RTKN2-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNMB4 Gene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Calcium-activated Channel Subfamily M Regulatory Beta Subunit 4
Chromosome: CHR12: 70760061 -70828072
Locus: 12q15
RTKN2 Gene Summary
The Rhotekin 2 (RTKN2) gene is located on chr10 :63952952-64028466 at 10q21.2.
Gene Name: Rhotekin 2
Chromosome: CHR10: 63952952 -64028466
Locus: 10q21.2
Gene Diseases
The KCNMB4 RTKN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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