KCNMB4-ALDH3B2 Fusion FISH Probe
The KCNMB4-ALDH3B2 Fusion FISH Probe is used to confirm a fusion of the KCNMB4 and ALDH3B2 genes. The fusion of the KCNMB4 and ALDH3B2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNMB4-ALDH3B2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KCNMB4-ALDH3B2-20-AQAQ | 20 (40 μL) | 200 μL |
|
ALDH3B2 Gene Summary
This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. Altered methylation patterns at this locus have been observed in spermatozoa derived from patients exhibiting reduced fecundity. [provided by RefSeq, Aug 2017]
Gene Name: Aldehyde Dehydrogenase 3 Family Member B2
Chromosome: CHR11: 67429632 -67448685
Locus: 11q13.2
KCNMB4 Gene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Calcium-activated Channel Subfamily M Regulatory Beta Subunit 4
Chromosome: CHR12: 70760061 -70828072
Locus: 12q15
Gene Diseases
The KCNMB4 ALDH3B2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|