KCNJ3-GALNT13 Fusion FISH Probe
The KCNJ3-GALNT13 Fusion FISH Probe is used to confirm a fusion of the KCNJ3 and GALNT13 genes. The fusion of the KCNJ3 and GALNT13 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCNJ3-GALNT13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-RERE | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-REOR | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-REGO | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-REGR | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-REAQ | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-ORRE | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-OROR | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-ORGO | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-ORAQ | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GORE | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GOOR | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GOGO | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GOAQ | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GROR | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GRGR | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-GRAQ | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-AQRE | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-AQOR | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-AQGO | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-AQGR | 20 (40 μL) | 200 μL |
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| KCNJ3-GALNT13-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNJ3 Gene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, May 2012]
Gene Name: Potassium Voltage-gated Channel Subfamily J Member 3
Chromosome: CHR2: 155555092 -155713014
Locus: 2q24.1
GALNT13 Gene Summary
The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM, Apr 2004]
Gene Name: Polypeptide N-acetylgalactosaminyltransferase 13
Chromosome: CHR2: 154728425 -155310489
Locus: 2q23.3-q24.1
Gene Diseases
The KCNJ3 GALNT13 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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