KCNJ10-CISD2 Fusion FISH Probe
The KCNJ10-CISD2 Fusion FISH Probe is used to confirm a fusion of the KCNJ10 and CISD2 genes. The fusion of the KCNJ10 and CISD2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCNJ10-CISD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-RERE | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-REOR | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-REGO | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-REGR | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-REAQ | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-ORRE | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-OROR | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-ORGO | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GORE | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GOOR | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GOGO | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GROR | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GRGR | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-AQRE | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-AQOR | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-AQGO | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-AQGR | 20 (40 μL) | 200 μL |
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| KCNJ10-CISD2-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNJ10 Gene Summary
This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Voltage-gated Channel Subfamily J Member 10
Chromosome: CHR1: 160007256 -160040051
Locus: 1q23.2
CISD2 Gene Summary
The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011]
Gene Name: CDGSH Iron Sulfur Domain 2
Chromosome: CHR4: 103790134 -103813963
Locus: 4q24
Gene Diseases
The KCNJ10 CISD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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