KALRN-CREB5 Fusion FISH Probe
The KALRN-CREB5 Fusion FISH Probe is used to confirm a fusion of the KALRN and CREB5 genes. The fusion of the KALRN and CREB5 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KALRN-CREB5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-RERE | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-REOR | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-REGO | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-REGR | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-REAQ | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-ORRE | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-OROR | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-ORGO | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-ORAQ | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GORE | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GOOR | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GOGO | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GOGR | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GOAQ | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GRRE | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GROR | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GRGO | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GRGR | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-GRAQ | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-AQRE | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-AQOR | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-AQGO | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-AQGR | 20 (40 μL) | 200 μL |
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| KALRN-CREB5-20-AQAQ | 20 (40 μL) | 200 μL |
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KALRN Gene Summary
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]
Gene Name: Kalirin RhoGEF Kinase
Chromosome: CHR3: 123813557 -124440036
Locus: 3q21.1-q21.2
CREB5 Gene Summary
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: CAMP Responsive Element Binding Protein 5
Chromosome: CHR7: 28338939 -28865511
Locus: 7p15.1
Gene Diseases
The KALRN CREB5 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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