JUP-CCT5 Fusion FISH Probe
The JUP-CCT5 Fusion FISH Probe is used to confirm a fusion of the JUP and CCT5 genes. The fusion of the JUP and CCT5 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| JUP-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| JUP-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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JUP Gene Summary
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]
Gene Name: Junction Plakoglobin
Chromosome: CHR17: 39910858 -39942964
Locus: 17q21.2
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The JUP CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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