JTB-CYP1B1 Fusion FISH Probe
The JTB-CYP1B1 Fusion FISH Probe is used to confirm a fusion of the JTB and CYP1B1 genes. The fusion of the JTB and CYP1B1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| JTB-CYP1B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-RERE | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-REOR | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-REGO | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-REGR | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-REAQ | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-ORRE | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-OROR | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-ORGO | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-ORAQ | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GORE | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GOOR | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GOGO | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GOGR | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GOAQ | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GRRE | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GROR | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GRGO | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GRGR | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-GRAQ | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-AQRE | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-AQOR | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-AQGO | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-AQGR | 20 (40 μL) | 200 μL |
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| JTB-CYP1B1-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP1B1 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Family 1 Subfamily B Member 1
Chromosome: CHR2: 38294745 -38303323
Locus: 2p22.2
JTB Gene Summary
The Jumping Translocation Breakpoint (JTB) gene is located on chr1 :153946744-153950451 at 1q21.3.
Gene Name: Jumping Translocation Breakpoint
Chromosome: CHR1: 153946744 -153950451
Locus: 1q21.3
Gene Diseases
The JTB CYP1B1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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