JAZF1-SNX13 Fusion FISH Probe
The JAZF1-SNX13 Fusion FISH Probe is used to confirm a fusion of the JAZF1 and SNX13 genes. The fusion of the JAZF1 and SNX13 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| JAZF1-SNX13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-RERE | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-REOR | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-REGO | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-REGR | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-REAQ | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-ORRE | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-OROR | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-ORGO | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-ORAQ | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GORE | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GOOR | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GOGO | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GOGR | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GOAQ | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GRRE | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GROR | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GRGO | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GRGR | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-GRAQ | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-AQRE | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-AQOR | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-AQGO | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-AQGR | 20 (40 μL) | 200 μL |
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| JAZF1-SNX13-20-AQAQ | 20 (40 μL) | 200 μL |
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SNX13 Gene Summary
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008]
Gene Name: Sorting Nexin 13
Chromosome: CHR7: 17830384 -17980131
Locus: 7p21.1
JAZF1 Gene Summary
This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008]
Gene Name: JAZF Zinc Finger 1
Chromosome: CHR7: 27870192 -28220437
Locus: 7p15.2-p15.1
Gene Diseases
The JAZF1 SNX13 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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