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JARID2-NEDD9 Fusion FISH Probe

The JARID2-NEDD9 Fusion FISH Probe is used to confirm a fusion of the JARID2 and NEDD9 genes. The fusion of the JARID2 and NEDD9 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
JARID2-NEDD9-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
JARID2-NEDD9-20-RERE 20 (40 μL) 200 μL
JARID2-NEDD9-20-REOR 20 (40 μL) 200 μL
JARID2-NEDD9-20-REGO 20 (40 μL) 200 μL
JARID2-NEDD9-20-REGR 20 (40 μL) 200 μL
JARID2-NEDD9-20-REAQ 20 (40 μL) 200 μL
JARID2-NEDD9-20-ORRE 20 (40 μL) 200 μL
JARID2-NEDD9-20-OROR 20 (40 μL) 200 μL
JARID2-NEDD9-20-ORGO 20 (40 μL) 200 μL
JARID2-NEDD9-20-ORAQ 20 (40 μL) 200 μL
JARID2-NEDD9-20-GORE 20 (40 μL) 200 μL
JARID2-NEDD9-20-GOOR 20 (40 μL) 200 μL
JARID2-NEDD9-20-GOGO 20 (40 μL) 200 μL
JARID2-NEDD9-20-GOGR 20 (40 μL) 200 μL
JARID2-NEDD9-20-GOAQ 20 (40 μL) 200 μL
JARID2-NEDD9-20-GRRE 20 (40 μL) 200 μL
JARID2-NEDD9-20-GROR 20 (40 μL) 200 μL
JARID2-NEDD9-20-GRGO 20 (40 μL) 200 μL
JARID2-NEDD9-20-GRGR 20 (40 μL) 200 μL
JARID2-NEDD9-20-GRAQ 20 (40 μL) 200 μL
JARID2-NEDD9-20-AQRE 20 (40 μL) 200 μL
JARID2-NEDD9-20-AQOR 20 (40 μL) 200 μL
JARID2-NEDD9-20-AQGO 20 (40 μL) 200 μL
JARID2-NEDD9-20-AQGR 20 (40 μL) 200 μL
JARID2-NEDD9-20-AQAQ 20 (40 μL) 200 μL

JARID2 Gene Summary

This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]

Gene Name: Jumonji And AT-rich Interaction Domain Containing 2

Chromosome: CHR6: 15246526 -15522253

Locus: 6p22.3

NEDD9 Gene Summary

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Gene Name: Neural Precursor Cell Expressed, Developmentally Down-regulated 9

Chromosome: CHR6: 11183530 -11382581

Locus: 6p24.2

Gene Diseases

The JARID2 NEDD9 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.