JARID2-HSD3B1 Fusion FISH Probe
The JARID2-HSD3B1 Fusion FISH Probe is used to confirm a fusion of the JARID2 and HSD3B1 genes. The fusion of the JARID2 and HSD3B1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| JARID2-HSD3B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-RERE | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-REOR | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-REGO | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-REGR | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-REAQ | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-ORRE | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-OROR | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-ORGO | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-ORAQ | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GORE | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GOOR | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GOGO | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GOGR | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GOAQ | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GRRE | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GROR | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GRGO | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GRGR | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-GRAQ | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-AQRE | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-AQOR | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-AQGO | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-AQGR | 20 (40 μL) | 200 μL |
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| JARID2-HSD3B1-20-AQAQ | 20 (40 μL) | 200 μL |
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HSD3B1 Gene Summary
The protein encoded by this gene is an enzyme that catalyzes the oxidative conversion of delta-5-3-beta-hydroxysteroid precursors into delta-4-ketosteroids, which leads to the production of all classes of steroid hormones. The encoded protein also catalyzes the interconversion of 3-beta-hydroxy- and 3-keto-5-alpha-androstane steroids. [provided by RefSeq, Jun 2016]
Gene Name: Hydroxy-delta-5-steroid Dehydrogenase, 3 Beta- And Steroid Delta-isomerase 1
Chromosome: CHR1: 120049825 -120057681
Locus: 1p12
JARID2 Gene Summary
This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
Gene Name: Jumonji And AT-rich Interaction Domain Containing 2
Chromosome: CHR6: 15246526 -15522253
Locus: 6p22.3
Gene Diseases
The JARID2 HSD3B1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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