JARID2-HIVEP1 Fusion FISH Probe
The JARID2-HIVEP1 Fusion FISH Probe is used to confirm a fusion of the JARID2 and HIVEP1 genes. The fusion of the JARID2 and HIVEP1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| JARID2-HIVEP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-RERE | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-REOR | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-REGO | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-REGR | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-REAQ | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-ORRE | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-OROR | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-ORGO | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GORE | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GOOR | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GOGO | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GOGR | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GRRE | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GROR | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GRGO | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GRGR | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-AQRE | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-AQOR | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-AQGO | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-AQGR | 20 (40 μL) | 200 μL |
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| JARID2-HIVEP1-20-AQAQ | 20 (40 μL) | 200 μL |
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HIVEP1 Gene Summary
This gene encodes a transcription factor belonging to the ZAS family, members of which are large proteins that contain a ZAS domain - a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specifically to the DNA sequence motif, GGGACTTTCC, found in the enhancer elements of several viral promoters, including human immunodeficiency virus (HIV), and to related sequences found in the enhancer elements of a number of cellular promoters. This protein binds to this sequence motif, suggesting a role in the transcriptional regulation of both viral and cellular genes. [provided by RefSeq, Oct 2011]
Gene Name: Human Immunodeficiency Virus Type I Enhancer Binding Protein 1
Chromosome: CHR6: 12012723 -12165232
Locus: 6p24.1
JARID2 Gene Summary
This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
Gene Name: Jumonji And AT-rich Interaction Domain Containing 2
Chromosome: CHR6: 15246526 -15522253
Locus: 6p22.3
Gene Diseases
The JARID2 HIVEP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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