JAK2-CSTF3 Fusion FISH Probe
The JAK2-CSTF3 Fusion FISH Probe is used to confirm a fusion of the JAK2 and CSTF3 genes. The fusion of the JAK2 and CSTF3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| JAK2-CSTF3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-RERE | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-REOR | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-REGO | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-REGR | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-REAQ | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-ORRE | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-OROR | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-ORGO | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-ORAQ | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GORE | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GOOR | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GOGO | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GOGR | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GOAQ | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GRRE | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GROR | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GRGO | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GRGR | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-GRAQ | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-AQRE | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-AQOR | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-AQGO | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-AQGR | 20 (40 μL) | 200 μL |
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| JAK2-CSTF3-20-AQAQ | 20 (40 μL) | 200 μL |
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CSTF3 Gene Summary
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Cleavage Stimulation Factor Subunit 3
Chromosome: CHR11: 33106129 -33183037
Locus: 11p13
JAK2 Gene Summary
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]
Gene Name: Janus Kinase 2
Chromosome: CHR9: 4985244 -5128183
Locus: 9p24.1
Gene Diseases
The JAK2 CSTF3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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