ITSN1-CHODL Fusion FISH Probe
The ITSN1-CHODL Fusion FISH Probe is used to confirm a fusion of the ITSN1 and CHODL genes. The fusion of the ITSN1 and CHODL genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ITSN1-CHODL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-RERE | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-REOR | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-REGO | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-REGR | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-REAQ | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-ORRE | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-OROR | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-ORGO | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-ORAQ | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GORE | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GOOR | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GOGO | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GOGR | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GOAQ | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GRRE | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GROR | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GRGO | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GRGR | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-GRAQ | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-AQRE | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-AQOR | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-AQGO | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-AQGR | 20 (40 μL) | 200 μL |
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| ITSN1-CHODL-20-AQAQ | 20 (40 μL) | 200 μL |
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ITSN1 Gene Summary
The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far. [provided by RefSeq, Jul 2008]
Gene Name: Intersectin 1
Chromosome: CHR21: 35014783 -35261609
Locus: 21q22.11
CHODL Gene Summary
This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Gene Name: Chondrolectin
Chromosome: CHR21: 19289656 -19639687
Locus: 21q21.1
Gene Diseases
The ITSN1 CHODL Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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