ITPR1-SETMAR Fusion FISH Probe
The ITPR1-SETMAR Fusion FISH Probe is used to confirm a fusion of the ITPR1 and SETMAR genes. The fusion of the ITPR1 and SETMAR genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITPR1-SETMAR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ITPR1-SETMAR-20-AQAQ | 20 (40 μL) | 200 μL |
|
ITPR1 Gene Summary
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]
Gene Name: Inositol 1,4,5-trisphosphate Receptor Type 1
Chromosome: CHR3: 4535031 -4889524
Locus: 3p26.1
SETMAR Gene Summary
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Name: SET Domain And Mariner Transposase Fusion Gene
Chromosome: CHR3: 4344987 -4358949
Locus: 3p26.1
Gene Diseases
The ITPR1 SETMAR Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|