ITM2C-TYK2 Fusion FISH Probe
The ITM2C-TYK2 Fusion FISH Probe is used to confirm a fusion of the ITM2C and TYK2 genes. The fusion of the ITM2C and TYK2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ITM2C-TYK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-RERE | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-REOR | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-REGO | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-REGR | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-REAQ | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-ORRE | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-OROR | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-ORGO | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GORE | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GOOR | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GOGO | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GOGR | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GRRE | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GROR | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GRGO | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GRGR | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-AQRE | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-AQOR | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-AQGO | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-AQGR | 20 (40 μL) | 200 μL |
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| ITM2C-TYK2-20-AQAQ | 20 (40 μL) | 200 μL |
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TYK2 Gene Summary
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
Gene Name: Tyrosine Kinase 2
Chromosome: CHR19: 10461203 -10491248
Locus: 19p13.2
ITM2C Gene Summary
The Integral Membrane Protein 2C (ITM2C) gene is located on chr2 :231729620-231743963 at 2q37.1.
Gene Name: Integral Membrane Protein 2C
Chromosome: CHR2: 231729620 -231743963
Locus: 2q37.1
Gene Diseases
The ITM2C TYK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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