ITGB5-ZNF148 Fusion FISH Probe
The ITGB5-ZNF148 Fusion FISH Probe is used to confirm a fusion of the ITGB5 and ZNF148 genes. The fusion of the ITGB5 and ZNF148 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ITGB5-ZNF148-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-RERE | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-REOR | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-REGO | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-REGR | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-REAQ | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-ORRE | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-OROR | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-ORGO | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-ORAQ | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GORE | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GOOR | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GOGO | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GOGR | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GOAQ | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GRRE | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GROR | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GRGO | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GRGR | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-GRAQ | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-AQRE | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-AQOR | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-AQGO | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-AQGR | 20 (40 μL) | 200 μL |
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| ITGB5-ZNF148-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGB5 Gene Summary
This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]
Gene Name: Integrin Subunit Beta 5
Chromosome: CHR3: 124481794 -124606144
Locus: 3q21.2
ZNF148 Gene Summary
The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. [provided by RefSeq, Feb 2017]
Gene Name: Zinc Finger Protein 148
Chromosome: CHR3: 124944512 -125094198
Locus: 3q21.2
Gene Diseases
The ITGB5 ZNF148 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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