ITGB1-DYM Fusion FISH Probe
The ITGB1-DYM Fusion FISH Probe is used to confirm a fusion of the ITGB1 and DYM genes. The fusion of the ITGB1 and DYM genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ITGB1-DYM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-RERE | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-REOR | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-REGO | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-REGR | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-REAQ | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-ORRE | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-OROR | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-ORGO | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-ORAQ | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GORE | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GOOR | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GOGO | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GOGR | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GOAQ | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GRRE | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GROR | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GRGO | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GRGR | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-GRAQ | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-AQRE | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-AQOR | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-AQGO | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-AQGR | 20 (40 μL) | 200 μL |
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| ITGB1-DYM-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGB1 Gene Summary
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Integrin Subunit Beta 1
Chromosome: CHR10: 33189245 -33247293
Locus: 10p11.22
DYM Gene Summary
This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]
Gene Name: Dymeclin
Chromosome: CHR18: 46570171 -46987079
Locus: 18q21.1
Gene Diseases
The ITGB1 DYM Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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