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ITGAV-ARHGAP15 Fusion FISH Probe

The ITGAV-ARHGAP15 Fusion FISH Probe is used to confirm a fusion of the ITGAV and ARHGAP15 genes. The fusion of the ITGAV and ARHGAP15 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ITGAV-ARHGAP15-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-RERE 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-REOR 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-REGO 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-REGR 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-REAQ 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-ORRE 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-OROR 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-ORGO 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-ORAQ 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GORE 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GOOR 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GOGO 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GOGR 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GOAQ 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GRRE 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GROR 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GRGO 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GRGR 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-GRAQ 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-AQRE 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-AQOR 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-AQGO 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-AQGR 20 (40 μL) 200 μL
ITGAV-ARHGAP15-20-AQAQ 20 (40 μL) 200 μL

ITGAV Gene Summary

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]

Gene Name: Integrin Subunit Alpha V

Chromosome: CHR2: 187454789 -187545628

Locus: 2q32.1

ARHGAP15 Gene Summary

RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]

Gene Name: Rho GTPase Activating Protein 15

Chromosome: CHR2: 143886898 -144525921

Locus: 2q22.2-q22.3

Gene Diseases

The ITGAV ARHGAP15 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.