ITGAV-ARHGAP15 Fusion FISH Probe
The ITGAV-ARHGAP15 Fusion FISH Probe is used to confirm a fusion of the ITGAV and ARHGAP15 genes. The fusion of the ITGAV and ARHGAP15 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGAV-ARHGAP15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ITGAV-ARHGAP15-20-AQAQ | 20 (40 μL) | 200 μL |
|
ITGAV Gene Summary
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Gene Name: Integrin Subunit Alpha V
Chromosome: CHR2: 187454789 -187545628
Locus: 2q32.1
ARHGAP15 Gene Summary
RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]
Gene Name: Rho GTPase Activating Protein 15
Chromosome: CHR2: 143886898 -144525921
Locus: 2q22.2-q22.3
Gene Diseases
The ITGAV ARHGAP15 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|