ITGA5-GTSF1 Fusion FISH Probe
The ITGA5-GTSF1 Fusion FISH Probe is used to confirm a fusion of the ITGA5 and GTSF1 genes. The fusion of the ITGA5 and GTSF1 genes has been associated with Lung Squamous Cell Carcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ITGA5-GTSF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-RERE | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-REOR | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-REGO | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-REGR | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-REAQ | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-ORRE | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-OROR | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-ORGO | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GORE | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GOOR | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GOGO | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GOGR | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GRRE | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GROR | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GRGO | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GRGR | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-AQRE | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-AQOR | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-AQGO | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-AQGR | 20 (40 μL) | 200 μL |
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| ITGA5-GTSF1-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGA5 Gene Summary
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Gene Name: Integrin Subunit Alpha 5
Chromosome: CHR12: 54789044 -54813050
Locus: 12q13.13
GTSF1 Gene Summary
The Gametocyte Specific Factor 1 (GTSF1) gene is located on chr12 :54849735-54867386 at 12q13.13.
Gene Name: Gametocyte Specific Factor 1
Chromosome: CHR12: 54849735 -54867386
Locus: 12q13.13
Gene Diseases
The ITGA5 GTSF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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