ITGA4-UBE2E2 Fusion FISH Probe
The ITGA4-UBE2E2 Fusion FISH Probe is used to confirm a fusion of the ITGA4 and UBE2E2 genes. The fusion of the ITGA4 and UBE2E2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ITGA4-UBE2E2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-RERE | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-REOR | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-REGO | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-REGR | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-REAQ | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-ORRE | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-OROR | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-ORGO | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GORE | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GOOR | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GOGO | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GOGR | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GRRE | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GROR | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GRGO | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GRGR | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-AQRE | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-AQOR | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-AQGO | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-AQGR | 20 (40 μL) | 200 μL |
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| ITGA4-UBE2E2-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGA4 Gene Summary
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Gene Name: Integrin Subunit Alpha 4
Chromosome: CHR2: 182321618 -182402468
Locus: 2q31.3
UBE2E2 Gene Summary
The Ubiquitin Conjugating Enzyme E2 E2 (UBE2E2) gene is located on chr3 :23244783-23632296 at 3p24.3.
Gene Name: Ubiquitin Conjugating Enzyme E2 E2
Chromosome: CHR3: 23244783 -23632296
Locus: 3p24.3
Gene Diseases
The ITGA4 UBE2E2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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