ITGA3-EIF2AK2 Fusion FISH Probe
The ITGA3-EIF2AK2 Fusion FISH Probe is used to confirm a fusion of the ITGA3 and EIF2AK2 genes. The fusion of the ITGA3 and EIF2AK2 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGA3-EIF2AK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ITGA3-EIF2AK2-20-AQAQ | 20 (40 μL) | 200 μL |
|
ITGA3 Gene Summary
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]
Gene Name: Integrin Subunit Alpha 3
Chromosome: CHR17: 48133339 -48167849
Locus: 17q21.33
EIF2AK2 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2
Chromosome: CHR2: 37333698 -37384190
Locus: 2p22.2
Gene Diseases
The ITGA3 EIF2AK2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|