ITGA2-RNF180 Fusion FISH Probe
The ITGA2-RNF180 Fusion FISH Probe is used to confirm a fusion of the ITGA2 and RNF180 genes. The fusion of the ITGA2 and RNF180 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ITGA2-RNF180-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-RERE | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-REOR | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-REGO | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-REGR | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-REAQ | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-ORRE | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-OROR | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-ORGO | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-ORAQ | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GORE | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GOOR | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GOGO | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GOGR | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GOAQ | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GRRE | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GROR | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GRGO | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GRGR | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-GRAQ | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-AQRE | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-AQOR | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-AQGO | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-AQGR | 20 (40 μL) | 200 μL |
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| ITGA2-RNF180-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGA2 Gene Summary
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Name: Integrin Subunit Alpha 2
Chromosome: CHR5: 52285155 -52390609
Locus: 5q11.2
RNF180 Gene Summary
The Ring Finger Protein 180 (RNF180) gene is located on chr5 :63461670-63668696 at 5q12.3.
Gene Name: Ring Finger Protein 180
Chromosome: CHR5: 63461670 -63668696
Locus: 5q12.3
Gene Diseases
The ITGA2 RNF180 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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