ITGA10-PEX11B Fusion FISH Probe
The ITGA10-PEX11B Fusion FISH Probe is used to confirm a fusion of the ITGA10 and PEX11B genes. The fusion of the ITGA10 and PEX11B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ITGA10-PEX11B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-RERE | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-REOR | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-REGO | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-REGR | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-REAQ | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-ORRE | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-OROR | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-ORGO | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GORE | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GOOR | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GOGO | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GOGR | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GRRE | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GROR | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GRGO | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GRGR | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-AQRE | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-AQOR | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-AQGO | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-AQGR | 20 (40 μL) | 200 μL |
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| ITGA10-PEX11B-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGA10 Gene Summary
Integrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell-surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP-2epsilon and Ets-1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: Integrin Subunit Alpha 10
Chromosome: CHR1: 145524989 -145543868
Locus: 1q21.1
PEX11B Gene Summary
The protein encoded by this gene facilitates peroxisomal proliferation and interacts with PEX19. The encoded protein is found in the peroxisomal membrane. Several transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Name: Peroxisomal Biogenesis Factor 11 Beta
Chromosome: CHR1: 145516164 -145523732
Locus: 1q21.1
Gene Diseases
The ITGA10 PEX11B Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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