IQSEC1-GSTM3 Fusion FISH Probe
The IQSEC1-GSTM3 Fusion FISH Probe is used to confirm a fusion of the IQSEC1 and GSTM3 genes. The fusion of the IQSEC1 and GSTM3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IQSEC1-GSTM3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-RERE | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-REOR | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-REGO | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-REGR | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-REAQ | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-ORRE | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-OROR | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-ORGO | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-ORAQ | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GORE | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GOOR | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GOGO | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GOGR | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GOAQ | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GRRE | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GROR | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GRGO | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GRGR | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-GRAQ | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-AQRE | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-AQOR | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-AQGO | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-AQGR | 20 (40 μL) | 200 μL |
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| IQSEC1-GSTM3-20-AQAQ | 20 (40 μL) | 200 μL |
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GSTM3 Gene Summary
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
Gene Name: Glutathione S-transferase Mu 3
Chromosome: CHR1: 110276553 -110283660
Locus: 1p13.3
IQSEC1 Gene Summary
The IQ Motif And Sec7 Domain 1 (IQSEC1) gene is located on chr3 :12938718-13114617 at 3p25.2-p25.1.
Gene Name: IQ Motif And Sec7 Domain 1
Chromosome: CHR3: 12938718 -13114617
Locus: 3p25.2-p25.1
Gene Diseases
The IQSEC1 GSTM3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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