IQCB1-CACNG4 Fusion FISH Probe
The IQCB1-CACNG4 Fusion FISH Probe is used to confirm a fusion of the IQCB1 and CACNG4 genes. The fusion of the IQCB1 and CACNG4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IQCB1-CACNG4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-RERE | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-REOR | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-REGO | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-REGR | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-REAQ | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-ORRE | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-OROR | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-ORGO | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-ORAQ | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GORE | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GOOR | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GOGO | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GOGR | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GOAQ | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GRRE | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GROR | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GRGO | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GRGR | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-GRAQ | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-AQRE | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-AQOR | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-AQGO | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-AQGR | 20 (40 μL) | 200 μL |
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| IQCB1-CACNG4-20-AQAQ | 20 (40 μL) | 200 μL |
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IQCB1 Gene Summary
This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016]
Gene Name: IQ Motif Containing B1
Chromosome: CHR3: 121488609 -121553926
Locus: 3q21.1
CACNG4 Gene Summary
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Gamma 4
Chromosome: CHR17: 64960979 -65029518
Locus: 17q24.2
Gene Diseases
The IQCB1 CACNG4 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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