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IPO7-CTR9 Fusion FISH Probe

The IPO7-CTR9 Fusion FISH Probe is used to confirm a fusion of the IPO7 and CTR9 genes. The fusion of the IPO7 and CTR9 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
IPO7-CTR9-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
IPO7-CTR9-20-RERE 20 (40 μL) 200 μL
IPO7-CTR9-20-REOR 20 (40 μL) 200 μL
IPO7-CTR9-20-REGO 20 (40 μL) 200 μL
IPO7-CTR9-20-REGR 20 (40 μL) 200 μL
IPO7-CTR9-20-REAQ 20 (40 μL) 200 μL
IPO7-CTR9-20-ORRE 20 (40 μL) 200 μL
IPO7-CTR9-20-OROR 20 (40 μL) 200 μL
IPO7-CTR9-20-ORGO 20 (40 μL) 200 μL
IPO7-CTR9-20-ORAQ 20 (40 μL) 200 μL
IPO7-CTR9-20-GORE 20 (40 μL) 200 μL
IPO7-CTR9-20-GOOR 20 (40 μL) 200 μL
IPO7-CTR9-20-GOGO 20 (40 μL) 200 μL
IPO7-CTR9-20-GOGR 20 (40 μL) 200 μL
IPO7-CTR9-20-GOAQ 20 (40 μL) 200 μL
IPO7-CTR9-20-GRRE 20 (40 μL) 200 μL
IPO7-CTR9-20-GROR 20 (40 μL) 200 μL
IPO7-CTR9-20-GRGO 20 (40 μL) 200 μL
IPO7-CTR9-20-GRGR 20 (40 μL) 200 μL
IPO7-CTR9-20-GRAQ 20 (40 μL) 200 μL
IPO7-CTR9-20-AQRE 20 (40 μL) 200 μL
IPO7-CTR9-20-AQOR 20 (40 μL) 200 μL
IPO7-CTR9-20-AQGO 20 (40 μL) 200 μL
IPO7-CTR9-20-AQGR 20 (40 μL) 200 μL
IPO7-CTR9-20-AQAQ 20 (40 μL) 200 μL

CTR9 Gene Summary

The protein encoded by this gene is a component of the PAF1 complex, which associates with RNA polymerase II and functions in transcriptional regulation and elongation. This complex also plays a role in the modification of histones. [provided by RefSeq, Oct 2016]

Gene Name: CTR9 Homolog, Paf1/RNA Polymerase II Complex Component

Chromosome: CHR11: 10772810 -10801290

Locus: 11p15.4

IPO7 Gene Summary

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq, Jul 2008]

Gene Name: Importin 7

Chromosome: CHR11: 9406168 -9469674

Locus: 11p15.4

Gene Diseases

The IPO7 CTR9 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.