IPMK-CXCL12 Fusion FISH Probe
The IPMK-CXCL12 Fusion FISH Probe is used to confirm a fusion of the IPMK and CXCL12 genes. The fusion of the IPMK and CXCL12 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IPMK-CXCL12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-RERE | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-REOR | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-REGO | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-REGR | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-REAQ | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-ORRE | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-OROR | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-ORGO | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-ORAQ | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GORE | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GOOR | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GOGO | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GOGR | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GOAQ | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GRRE | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GROR | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GRGO | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GRGR | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-GRAQ | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-AQRE | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-AQOR | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-AQGO | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-AQGR | 20 (40 μL) | 200 μL |
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| IPMK-CXCL12-20-AQAQ | 20 (40 μL) | 200 μL |
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CXCL12 Gene Summary
This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Gene Name: C-X-C Motif Chemokine Ligand 12
Chromosome: CHR10: 44865604 -44880545
Locus: 10q11.21
IPMK Gene Summary
This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19. [provided by RefSeq, Dec 2010]
Gene Name: Inositol Polyphosphate Multikinase
Chromosome: CHR10: 59951277 -60027694
Locus: 10q21.1
Gene Diseases
The IPMK CXCL12 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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