IP6K2-RHOA Fusion FISH Probe
The IP6K2-RHOA Fusion FISH Probe is used to confirm a fusion of the IP6K2 and RHOA genes. The fusion of the IP6K2 and RHOA genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IP6K2-RHOA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-RERE | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-REOR | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-REGR | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-OROR | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| IP6K2-RHOA-20-AQAQ | 20 (40 μL) | 200 μL |
|
RHOA Gene Summary
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
Gene Name: Ras Homolog Family Member A
Chromosome: CHR3: 49396578 -49449526
Locus: 3p21.31
IP6K2 Gene Summary
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Inositol Hexakisphosphate Kinase 2
Chromosome: CHR3: 48725435 -48754711
Locus: 3p21.31
Gene Diseases
The IP6K2 RHOA Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|