IP6K1-UBA7 Fusion FISH Probe
The IP6K1-UBA7 Fusion FISH Probe is used to confirm a fusion of the IP6K1 and UBA7 genes. The fusion of the IP6K1 and UBA7 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IP6K1-UBA7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-RERE | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-REOR | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-REGO | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-REGR | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-REAQ | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-ORRE | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-OROR | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-ORGO | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-ORAQ | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GORE | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GOOR | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GOGO | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GOGR | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GOAQ | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GRRE | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GROR | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GRGO | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GRGR | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-GRAQ | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-AQRE | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-AQOR | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-AQGO | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-AQGR | 20 (40 μL) | 200 μL |
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| IP6K1-UBA7-20-AQAQ | 20 (40 μL) | 200 μL |
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UBA7 Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Like Modifier Activating Enzyme 7
Chromosome: CHR3: 49842637 -49851391
Locus: 3p21.31
IP6K1 Gene Summary
This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]
Gene Name: Inositol Hexakisphosphate Kinase 1
Chromosome: CHR3: 49761727 -49823973
Locus: 3p21.31
Gene Diseases
The IP6K1 UBA7 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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