IP6K1-HYAL3 Fusion FISH Probe
The IP6K1-HYAL3 Fusion FISH Probe is used to confirm a fusion of the IP6K1 and HYAL3 genes. The fusion of the IP6K1 and HYAL3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IP6K1-HYAL3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-RERE | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-REOR | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-REGO | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-REGR | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-REAQ | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-ORRE | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-OROR | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-ORGO | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-ORAQ | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GORE | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GOOR | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GOGO | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GOGR | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GOAQ | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GRRE | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GROR | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GRGO | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GRGR | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-GRAQ | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-AQRE | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-AQOR | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-AQGO | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-AQGR | 20 (40 μL) | 200 μL |
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| IP6K1-HYAL3-20-AQAQ | 20 (40 μL) | 200 μL |
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HYAL3 Gene Summary
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]
Gene Name: Hyaluronoglucosaminidase 3
Chromosome: CHR3: 50330258 -50336899
Locus: 3p21.31
IP6K1 Gene Summary
This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]
Gene Name: Inositol Hexakisphosphate Kinase 1
Chromosome: CHR3: 49761727 -49823973
Locus: 3p21.31
Gene Diseases
The IP6K1 HYAL3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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