INTS8-ESRP1 Fusion FISH Probe
The INTS8-ESRP1 Fusion FISH Probe is used to confirm a fusion of the INTS8 and ESRP1 genes. The fusion of the INTS8 and ESRP1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| INTS8-ESRP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-RERE | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-REOR | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-REGO | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-REGR | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-REAQ | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-ORRE | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-OROR | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-ORGO | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GORE | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GOOR | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GOGO | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GOGR | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GRRE | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GROR | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GRGO | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GRGR | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-AQRE | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-AQOR | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-AQGO | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-AQGR | 20 (40 μL) | 200 μL |
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| INTS8-ESRP1-20-AQAQ | 20 (40 μL) | 200 μL |
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ESRP1 Gene Summary
ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009]
Gene Name: Epithelial Splicing Regulatory Protein 1
Chromosome: CHR8: 95653363 -95719694
Locus: 8q22.1
INTS8 Gene Summary
This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Name: Integrator Complex Subunit 8
Chromosome: CHR8: 95835533 -95892721
Locus: 8q22.1
Gene Diseases
The INTS8 ESRP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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