INTS4-NARS2 Fusion FISH Probe
The INTS4-NARS2 Fusion FISH Probe is used to confirm a fusion of the INTS4 and NARS2 genes. The fusion of the INTS4 and NARS2 genes has been associated with Ovarian Serous Cystadenocarcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| INTS4-NARS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-RERE | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-REOR | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-REGO | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-REGR | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-REAQ | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-ORRE | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-OROR | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-ORGO | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GORE | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GOOR | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GOGO | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GOGR | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GRRE | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GROR | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GRGO | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GRGR | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-AQRE | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-AQOR | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-AQGO | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-AQGR | 20 (40 μL) | 200 μL |
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| INTS4-NARS2-20-AQAQ | 20 (40 μL) | 200 μL |
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NARS2 Gene Summary
This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24). [provided by RefSeq, Mar 2015]
Gene Name: Asparaginyl-tRNA Synthetase 2, Mitochondrial
Chromosome: CHR11: 78147006 -78285909
Locus: 11q14.1
INTS4 Gene Summary
INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Name: Integrator Complex Subunit 4
Chromosome: CHR11: 77589765 -77705717
Locus: 11q14.1
Gene Diseases
The INTS4 NARS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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